A Cell Growth Model Revisited

In this paper a stochastic model for the simultaneous growth and division of a cell-population cohort structured by size is formulated. This shows that the functional differential equation which describes the steady form of the steady-size distribution which is approached asymptotically and sati...

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Main Authors: Derfel, G, van Brunt, B, Wake, G
Format: Journal article
Published: 2009
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author Derfel, G
van Brunt, B
Wake, G
author_facet Derfel, G
van Brunt, B
Wake, G
author_sort Derfel, G
collection OXFORD
description In this paper a stochastic model for the simultaneous growth and division of a cell-population cohort structured by size is formulated. This shows that the functional differential equation which describes the steady form of the steady-size distribution which is approached asymptotically and satisfies the well-known pantograph equation is more simply derived via a Poisson process. This firmly establishes the existence of the steady-size distribution and gives a form for it in terms of a sequence of probability distribution functions. Also it shows that the pantograph equation is a key equation for other situations where there is a distinct stochastic framework.
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spelling oxford-uuid:7a7c7ec7-dc5b-421b-a738-9897ce15fbac2022-03-26T20:44:24ZA Cell Growth Model RevisitedJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7a7c7ec7-dc5b-421b-a738-9897ce15fbacMathematical Institute - ePrints2009Derfel, Gvan Brunt, BWake, G In this paper a stochastic model for the simultaneous growth and division of a cell-population cohort structured by size is formulated. This shows that the functional differential equation which describes the steady form of the steady-size distribution which is approached asymptotically and satisfies the well-known pantograph equation is more simply derived via a Poisson process. This firmly establishes the existence of the steady-size distribution and gives a form for it in terms of a sequence of probability distribution functions. Also it shows that the pantograph equation is a key equation for other situations where there is a distinct stochastic framework.
spellingShingle Derfel, G
van Brunt, B
Wake, G
A Cell Growth Model Revisited
title A Cell Growth Model Revisited
title_full A Cell Growth Model Revisited
title_fullStr A Cell Growth Model Revisited
title_full_unstemmed A Cell Growth Model Revisited
title_short A Cell Growth Model Revisited
title_sort cell growth model revisited
work_keys_str_mv AT derfelg acellgrowthmodelrevisited
AT vanbruntb acellgrowthmodelrevisited
AT wakeg acellgrowthmodelrevisited
AT derfelg cellgrowthmodelrevisited
AT vanbruntb cellgrowthmodelrevisited
AT wakeg cellgrowthmodelrevisited