Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF.
The porins OmpF and OmpC are trimeric β-barrel proteins with narrow channels running through each monomer that exclude molecules > 600 Da while mediating the passive diffusion of small nutrients and metabolites across the Gram-negative outer membrane (OM). Here, we elucidate the mechanism by...
Autors principals: | Housden, N, Wojdyla, J, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A, Kleanthous, K |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2010
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