Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF.

The porins OmpF and OmpC are trimeric β-barrel proteins with narrow channels running through each monomer that exclude molecules > 600 Da while mediating the passive diffusion of small nutrients and metabolites across the Gram-negative outer membrane (OM). Here, we elucidate the mechanism by...

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Dettagli Bibliografici
Autori principali: Housden, N, Wojdyla, J, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A, Kleanthous, K
Natura: Journal article
Lingua:English
Pubblicazione: 2010