Estimation of the in-vivo minimum inhibitory concentration of cipargamin in uncomplicated Plasmodium falciparum malaria

The minimum inhibitory concentration (MIC) of an antimalarial drug for a particular infection is the drug level associated with a net parasite multiplication rate of one per asexual cycle. To ensure cure of malaria the MIC must be exceeded until all parasites have been eliminated. The development of...

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Hlavní autoři: Tinh Tran, H, White, N, Thanh Nguyen, T, Toa Nhu, H, Duc Phung, T, Tarning, J, Nosten, F, Magnusson, B, Prakash Jain, J, Hamed, K
Médium: Journal article
Vydáno: American Society for Microbiology 2016