How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy

Heavily calcified and densely fibrotic coronary lesions continue to represent a challenge for percutaneous coronary intervention (PCI), as they are difficult to dilate, and it is difficult to deliver and implant drug-eluting stents (DES) properly. Poor stent deployment is associated with high rates...

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Автори: Kassimis, G, Raina, T, Kontogiannis, N, Patri, G, Abramik, J, Zaphiriou, A, Banning, A
Формат: Journal article
Мова:English
Опубліковано: Elsevier 2019
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author Kassimis, G
Raina, T
Kontogiannis, N
Patri, G
Abramik, J
Zaphiriou, A
Banning, A
author_facet Kassimis, G
Raina, T
Kontogiannis, N
Patri, G
Abramik, J
Zaphiriou, A
Banning, A
author_sort Kassimis, G
collection OXFORD
description Heavily calcified and densely fibrotic coronary lesions continue to represent a challenge for percutaneous coronary intervention (PCI), as they are difficult to dilate, and it is difficult to deliver and implant drug-eluting stents (DES) properly. Poor stent deployment is associated with high rates of periprocedural complications and suboptimal long-term clinical outcomes. Thanks to the introduction of several adjunctive PCI tools, like cutting and scoring balloons, atherectomy devices, and to the novel intravascular lithotripsy technology, the treatment of such lesions has become increasingly feasible, predictable and safe. A step-wise progression of strategies is described for coronary plaque modification, from well-recognised techniques to techniques that should only be considered when standard manoeuvres have proven unsuccessful. We highlight these techniques in the setting of clinical examples how best to apply them through better patient and lesion selection, with the main objective of optimising DES delivery and implantation, and subsequent improved outcomes.
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spelling oxford-uuid:7ab35c04-535c-49bf-9b38-7bfa5f48f6442022-03-26T20:45:43ZHow should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7ab35c04-535c-49bf-9b38-7bfa5f48f644EnglishSymplectic Elements at OxfordElsevier2019Kassimis, GRaina, TKontogiannis, NPatri, GAbramik, JZaphiriou, ABanning, AHeavily calcified and densely fibrotic coronary lesions continue to represent a challenge for percutaneous coronary intervention (PCI), as they are difficult to dilate, and it is difficult to deliver and implant drug-eluting stents (DES) properly. Poor stent deployment is associated with high rates of periprocedural complications and suboptimal long-term clinical outcomes. Thanks to the introduction of several adjunctive PCI tools, like cutting and scoring balloons, atherectomy devices, and to the novel intravascular lithotripsy technology, the treatment of such lesions has become increasingly feasible, predictable and safe. A step-wise progression of strategies is described for coronary plaque modification, from well-recognised techniques to techniques that should only be considered when standard manoeuvres have proven unsuccessful. We highlight these techniques in the setting of clinical examples how best to apply them through better patient and lesion selection, with the main objective of optimising DES delivery and implantation, and subsequent improved outcomes.
spellingShingle Kassimis, G
Raina, T
Kontogiannis, N
Patri, G
Abramik, J
Zaphiriou, A
Banning, A
How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title_full How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title_fullStr How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title_full_unstemmed How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title_short How should we treat heavily calcified coronary artery disease in contemporary practice? From atherectomy to intravascular lithotripsy
title_sort how should we treat heavily calcified coronary artery disease in contemporary practice from atherectomy to intravascular lithotripsy
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