Reaching the end-game for GWAS: Machine learning approaches for the prioritization of complex disease loci

Genome-wide association studies (GWAS) have revealed thousands of genetic loci that underpin the complex biology of many human traits. However, the strength of GWAS – the ability to detect genetic association by linkage disequilibrium (LD) – is also its limitation. Whilst the ever-increasing study s...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Nicholls, HL, John, CR, Watson, DS, Munroe, PB, Barnes, MR, Cabrera, CP
स्वरूप: Journal article
भाषा:English
प्रकाशित: Frontiers 2020