Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

BACKGROUND: Dihydroartemisinin-piperaquine (DP) is a new and relatively inexpensive artemisinin-containing fixed-combination antimalarial treatment. An adult treatment course contained 6.4 mg/kg dihydroartemisinin (DHA), which is >40% lower than the level in most artemisinin-containing combi...

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Autors principals: Ashley, E, Krudsood, S, Phaiphun, L, Srivilairit, S, Mcgready, R, Leowattana, W, Hutagalung, R, Wilairatana, P, Brockman, A, Looareesuwan, S, Nosten, F, White, N
Format: Journal article
Idioma:English
Publicat: 2004