Palladium-mediated cell-surface labeling.
Benign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free ca...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2012
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| _version_ | 1826280586205986816 |
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| author | Spicer, C Triemer, T Davis, B |
| author_facet | Spicer, C Triemer, T Davis, B |
| author_sort | Spicer, C |
| collection | OXFORD |
| description | Benign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free catalyst caused no cell death at required Pd loadings, suggesting future in vivo application of catalytic metal-mediated bond formation in more complex organisms. |
| first_indexed | 2024-03-07T00:15:54Z |
| format | Journal article |
| id | oxford-uuid:7ad30bc8-9cb7-422c-8b55-701eed5d18df |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:15:54Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:7ad30bc8-9cb7-422c-8b55-701eed5d18df2022-03-26T20:46:33ZPalladium-mediated cell-surface labeling.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7ad30bc8-9cb7-422c-8b55-701eed5d18dfEnglishSymplectic Elements at Oxford2012Spicer, CTriemer, TDavis, BBenign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free catalyst caused no cell death at required Pd loadings, suggesting future in vivo application of catalytic metal-mediated bond formation in more complex organisms. |
| spellingShingle | Spicer, C Triemer, T Davis, B Palladium-mediated cell-surface labeling. |
| title | Palladium-mediated cell-surface labeling. |
| title_full | Palladium-mediated cell-surface labeling. |
| title_fullStr | Palladium-mediated cell-surface labeling. |
| title_full_unstemmed | Palladium-mediated cell-surface labeling. |
| title_short | Palladium-mediated cell-surface labeling. |
| title_sort | palladium mediated cell surface labeling |
| work_keys_str_mv | AT spicerc palladiummediatedcellsurfacelabeling AT triemert palladiummediatedcellsurfacelabeling AT davisb palladiummediatedcellsurfacelabeling |