Palladium-mediated cell-surface labeling.

Benign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free ca...

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Main Authors: Spicer, C, Triemer, T, Davis, B
Format: Journal article
Jezik:English
Izdano: 2012
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author Spicer, C
Triemer, T
Davis, B
author_facet Spicer, C
Triemer, T
Davis, B
author_sort Spicer, C
collection OXFORD
description Benign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free catalyst caused no cell death at required Pd loadings, suggesting future in vivo application of catalytic metal-mediated bond formation in more complex organisms.
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institution University of Oxford
language English
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publishDate 2012
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spelling oxford-uuid:7ad30bc8-9cb7-422c-8b55-701eed5d18df2022-03-26T20:46:33ZPalladium-mediated cell-surface labeling.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7ad30bc8-9cb7-422c-8b55-701eed5d18dfEnglishSymplectic Elements at Oxford2012Spicer, CTriemer, TDavis, BBenign C-C bond formation at various sites in cell-surface channels has been achieved through Suzuki-Miyaura coupling of genetically positioned unnatural amino acids containing aryl halide side chains. This enabled site-selective cell surface manipulation of Escherichia coli ; the phosphine-free catalyst caused no cell death at required Pd loadings, suggesting future in vivo application of catalytic metal-mediated bond formation in more complex organisms.
spellingShingle Spicer, C
Triemer, T
Davis, B
Palladium-mediated cell-surface labeling.
title Palladium-mediated cell-surface labeling.
title_full Palladium-mediated cell-surface labeling.
title_fullStr Palladium-mediated cell-surface labeling.
title_full_unstemmed Palladium-mediated cell-surface labeling.
title_short Palladium-mediated cell-surface labeling.
title_sort palladium mediated cell surface labeling
work_keys_str_mv AT spicerc palladiummediatedcellsurfacelabeling
AT triemert palladiummediatedcellsurfacelabeling
AT davisb palladiummediatedcellsurfacelabeling