Glycosylation catalyzed by a chiral Bronsted acid.

The use of a chiral Brønsted acid catalyst for the activation of trichloroacetimidate glycosyl donors has been demonstrated for the first time. In toluene the chirality of the acid catalyst is seen to influence the stereochemical outcome of the glycosylation processes, hinting that perhaps diastereo...

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Bibliografische gegevens
Hoofdauteurs: Cox, D, Smith, M, Fairbanks, A
Formaat: Journal article
Taal:English
Gepubliceerd in: 2010
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author Cox, D
Smith, M
Fairbanks, A
author_facet Cox, D
Smith, M
Fairbanks, A
author_sort Cox, D
collection OXFORD
description The use of a chiral Brønsted acid catalyst for the activation of trichloroacetimidate glycosyl donors has been demonstrated for the first time. In toluene the chirality of the acid catalyst is seen to influence the stereochemical outcome of the glycosylation processes, hinting that perhaps diastereocontrol of glycosylation processes may become achievable through the judicious use of chiral organic catalysts.
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spelling oxford-uuid:7adebeaa-1a57-4938-9ac0-5ed6c782fd8c2022-03-26T20:46:54ZGlycosylation catalyzed by a chiral Bronsted acid.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7adebeaa-1a57-4938-9ac0-5ed6c782fd8cEnglishSymplectic Elements at Oxford2010Cox, DSmith, MFairbanks, AThe use of a chiral Brønsted acid catalyst for the activation of trichloroacetimidate glycosyl donors has been demonstrated for the first time. In toluene the chirality of the acid catalyst is seen to influence the stereochemical outcome of the glycosylation processes, hinting that perhaps diastereocontrol of glycosylation processes may become achievable through the judicious use of chiral organic catalysts.
spellingShingle Cox, D
Smith, M
Fairbanks, A
Glycosylation catalyzed by a chiral Bronsted acid.
title Glycosylation catalyzed by a chiral Bronsted acid.
title_full Glycosylation catalyzed by a chiral Bronsted acid.
title_fullStr Glycosylation catalyzed by a chiral Bronsted acid.
title_full_unstemmed Glycosylation catalyzed by a chiral Bronsted acid.
title_short Glycosylation catalyzed by a chiral Bronsted acid.
title_sort glycosylation catalyzed by a chiral bronsted acid
work_keys_str_mv AT coxd glycosylationcatalyzedbyachiralbronstedacid
AT smithm glycosylationcatalyzedbyachiralbronstedacid
AT fairbanksa glycosylationcatalyzedbyachiralbronstedacid