Pre-synaptic NO-cGMP pathway modulates vagal control of heart rate in isolated adult guinea pig atria.

Pre-synaptic NO-cGMP pathway modulates vagal control of heart rate in isolated adult guinea pig atria.

The role of nitric oxide (NO) in the vagal modulation of heart rate (HR) is controversial. We tested the hypothesis that NO acts via a pre-synaptic, guanylyl cyclase (GC) dependent pathway. The effects of inhibiting NO synthase (NOS) and GC were evaluated in isolated atrial/right vagal nerve prepara...

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Autors principals:	Herring, N, Golding, S, Paterson, D
Format:	Journal article
Idioma:	English
Publicat:	2000

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