Malignant pleural effusions: management options

Malignant pleural effusion (MPE) represents advanced metastatic malignancy and is associated with poor median survival. Incidence remains high and continues to rise, in part due to changing population demographics. This therefore represents a significant health care burden. Management is predominant...

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Main Authors: McCracken, DJ, Porcel, JM, Rahman, NM
Format: Journal article
Language:English
Published: Thieme Publishing 2019
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author McCracken, DJ
Porcel, JM
Rahman, NM
author_facet McCracken, DJ
Porcel, JM
Rahman, NM
author_sort McCracken, DJ
collection OXFORD
description Malignant pleural effusion (MPE) represents advanced metastatic malignancy and is associated with poor median survival. Incidence remains high and continues to rise, in part due to changing population demographics. This therefore represents a significant health care burden. Management is predominantly palliative in nature and multiple interventions are available within conventional treatment paradigms, all of which are proven to result in statistically significant patient benefit. This article further explores the methods available in the management of MPE along with the pitfalls, complications, and alternatives. Recent advances within the field are discussed with an exploration of likely future directions, including the role of ultrasound as a prospective predictor and the role of intrapleural fibrinolytic therapy.
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spelling oxford-uuid:7afb0213-dfc9-48d3-9e76-61b082965a582022-03-26T20:47:41ZMalignant pleural effusions: management optionsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7afb0213-dfc9-48d3-9e76-61b082965a58EnglishSymplectic Elements at OxfordThieme Publishing2019McCracken, DJPorcel, JMRahman, NMMalignant pleural effusion (MPE) represents advanced metastatic malignancy and is associated with poor median survival. Incidence remains high and continues to rise, in part due to changing population demographics. This therefore represents a significant health care burden. Management is predominantly palliative in nature and multiple interventions are available within conventional treatment paradigms, all of which are proven to result in statistically significant patient benefit. This article further explores the methods available in the management of MPE along with the pitfalls, complications, and alternatives. Recent advances within the field are discussed with an exploration of likely future directions, including the role of ultrasound as a prospective predictor and the role of intrapleural fibrinolytic therapy.
spellingShingle McCracken, DJ
Porcel, JM
Rahman, NM
Malignant pleural effusions: management options
title Malignant pleural effusions: management options
title_full Malignant pleural effusions: management options
title_fullStr Malignant pleural effusions: management options
title_full_unstemmed Malignant pleural effusions: management options
title_short Malignant pleural effusions: management options
title_sort malignant pleural effusions management options
work_keys_str_mv AT mccrackendj malignantpleuraleffusionsmanagementoptions
AT porceljm malignantpleuraleffusionsmanagementoptions
AT rahmannm malignantpleuraleffusionsmanagementoptions