Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

The PIM family of serine/threonine kinases have become an attractive target for anti-cancer drug development, particularly for certain hematological malignancies. Here, we describe the discovery of a series of inhibitors of the PIM kinase family using a high throughput screening strategy. Through a...

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ग्रंथसूची विवरण
मुख्य लेखकों: Bataille, C, Brennan, M, Byrne, S, Davies, S, Durbin, M, Fedorov, O, Huber, K, Jones, A, Knapp, S, Liu, G, Nadali, A, Quevedo, C, Russell, A, Walker, R, Westwood, R, Wynne, G
स्वरूप: Journal article
भाषा:English
प्रकाशित: Elsevier 2017

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