Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

The PIM family of serine/threonine kinases have become an attractive target for anti-cancer drug development, particularly for certain hematological malignancies. Here, we describe the discovery of a series of inhibitors of the PIM kinase family using a high throughput screening strategy. Through a...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Bataille, C, Brennan, M, Byrne, S, Davies, S, Durbin, M, Fedorov, O, Huber, K, Jones, A, Knapp, S, Liu, G, Nadali, A, Quevedo, C, Russell, A, Walker, R, Westwood, R, Wynne, G
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2017