A composite biomarker using multiparametric magnetic resonance imaging and blood analytes accurately identifies patients with non-alcoholic steatohepatitis and significant fibrosis

Non-alcoholic steatohepatitis (NASH) is major health burden lacking effective pharmacological therapies. Clinical trials enrol patients with histologically-defined NAFLD (non-alcoholic fatty liver disease) activity score (NAS) ≥ 4 and Kleiner-Brunt fibrosis stage (F) ≥ 2; however, screen failure rat...

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Bibliographic Details
Main Authors: Dennis, A, Mouchti, S, Kelly, M, Fallowfield, JA, Hirschfield, G, Pavlides, M, Banerjee, R
Format: Journal article
Language:English
Published: Nature Research 2020