The role of chemokines in atherosclerosis: recent evidence from experimental models and population genetics.

The role of chemokines in atherosclerosis: recent evidence from experimental models and population genetics.

PURPOSE OF REVIEW: Atherosclerosis is an inflammatory disease process. This review discusses the recent genetic evidence from animal models and human populations that highlight the importance of chemokines in atherosclerosis. RECENT FINDINGS: CC-chemokine/CC-chemokine receptors (CCR), including CCR...

Descrición completa

Detalles Bibliográficos
Main Authors:	Bursill, C, Channon, K, Greaves, D
Formato:	Journal article
Idioma:	English
Publicado:	2004

Títulos similares

Chemokines, chemokine receptors and atherosclerosis
por: John, A, et al.
Publicado: (2005)

Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice
por: Bursill, C, et al.
Publicado: (2004)

Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
por: Bursill, C, et al.
Publicado: (2003)

Adenoviral delivery of a Cc-chemokine inhibitor, "35k," reduces macrophage recruitment and atherosclerosis in Apoe knockout mice
por: Bursill, C, et al.
Publicado: (2004)

Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo.
por: Bursill, C, et al.
Publicado: (2003)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
por: Bursill, C, et al.
Publicado: (2005)

Atherosclerosis: role of chemokines and macrophages.
por: Lucas, A, et al.
Publicado: (2001)

Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
por: Bursill, C, et al.
Publicado: (2006)

Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition.
por: Bursill, C, et al.
Publicado: (2009)

Broad spectrum adenoviral CC-chemokine blockade attenuates long term vein graft accelerated atherosclerosis in ApoE-knockout mice
por: Ali, Z, et al.
Publicado: (2007)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.
por: Ali, Z, et al.
Publicado: (2005)

Adenoviral-mediated delivery of a CC-chemokine inhibitor ('35K') attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
por: Bursill, C, et al.
Publicado: (2004)

Adenoviral gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice
por: Ali, Z, et al.
Publicado: (2004)

Adenoviral mediated delivery of a CC chemokine (CK) inhibitor ("35K") attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
por: Bursill, C, et al.
Publicado: (2004)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces macrophage recruitment and smooth muscle content in vein graft atherosclerosis in apolipoprotein E-knockout mice
por: Ali, Z, et al.
Publicado: (2005)

Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice.
por: Bursill, C, et al.
Publicado: (2004)

Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1).
por: Lucas, A, et al.
Publicado: (2003)

The Downstream Regulation of Chemokine Receptor Signalling: Implications for Atherosclerosis
por: Jyoti Patel, et al.
Publicado: (2013-01-01)

Inflammation and immune responses in atherosclerosis.
por: Greaves, D, et al.
Publicado: (2002)

P623RGS-1 modulates leukocyte trafficking in atherosclerosis and aortic aneurysm formation through chemokine receptor desensitisation.
por: Patel, J, et al.
Publicado: (2014)

Inflammatory Chemokines in Atherosclerosis
por: Selin Gencer, et al.
Publicado: (2021-01-01)

YIA5 RGS-1 Regulates Leukocyte Trafficking in Atherosclerosis and Aortic Aneurysm Formation through Chemokine Receptor Desensitisation.
por: Patel, J, et al.
Publicado: (2014)

Chemokine binding protein 'M3' limits atherosclerosis in apolipoprotein E-/- mice.
por: Dhanya Ravindran, et al.
Publicado: (2017-01-01)

Tetrahydrobiopterin-dependent eNOS coupling attenuates vein graft atherosclerosis through inhibition of MCP-1 mediated monocyte recruitment to sites of vascular injury
por: Ali, Z, et al.
Publicado: (2007)

Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines
por: McNeill, E, et al.
Publicado: (2010)

RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling
por: Patel, J, et al.
Publicado: (2015)

Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence.
por: Greaves, D, et al.
Publicado: (1998)

Increased eNOS coupling protects against vein graft accelerated atherosclerosis in ApoE-KO mice
por: Ali, Z, et al.
Publicado: (2006)

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
por: White, G, et al.
Publicado: (2011)

Platelets and their chemokines in atherosclerosis – clinical applications
por: Philipp evon Hundelshausen, et al.
Publicado: (2014-08-01)

Novel aspects of chemokine receptor signalling in cardiovascular inflammation
por: Patel, J, et al.
Publicado: (2018)

Magnetic resonance imaging of endothelial adhesion molecules in mouse atherosclerosis using dual-targeted microparticles of iron oxide.
por: McAteer, M, et al.
Publicado: (2008)

Chemokines and myeloid cell recruitment.
por: Greaves, D, et al.
Publicado: (2000)

CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis.
por: Ali, Z, et al.
Publicado: (2008)

The Role of CXCR3 and Associated Chemokines in the Development of Atherosclerosis and During Myocardial Infarction
por: Veronika Szentes, et al.
Publicado: (2018-08-01)

Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade
por: White, G, et al.
Publicado: (2010)

Abduction of chemokine elements by herpesviruses
por: Dairaghi, D, et al.
Publicado: (1998)

A new role for the regulator of G-protein signalling-1 (RGS-1) in the modulation of macrophage function in atherosclerosis
por: Patel, J, et al.
Publicado: (2010)

Fractalkine: one chemokine, many functions.
por: White, G, et al.
Publicado: (2009)

An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
por: Omar El Bounkari, et al.
Publicado: (2025-03-01)