Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.
BACKGROUND: Prostaglandin D2 (PGD2) and cysteinyl leukotrienes (cysLTs) are lipid mediators derived from mast cells, which activate TH2 cells. The combination of PGD2 and cysLTs (notably cysteinyl leukotriene E4 [LTE4]) enhances TH2 cytokine production. However, the synergistic interaction of cysLTs...
मुख्य लेखकों: | Xue, L, Fergusson, J, Salimi, M, Panse, I, Ussher, J, Hegazy, A, Vinall, S, Jackson, D, Hunter, MG, Pettipher, R, Ogg, G, Klenerman, P |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Elsevier
2015
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समान संसाधन
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Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2.
द्वारा: Xue, L, और अन्य
प्रकाशित: (2012) -
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
द्वारा: Xue, L, और अन्य
प्रकाशित: (2013) -
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.
द्वारा: Xue, L, और अन्य
प्रकाशित: (2014) -
Cysteinyl leukotriene E4 activates human ILC2s and enhances the effect of prostaglandin D2 and epithelial cytokines
द्वारा: Salimi, M, और अन्य
प्रकाशित: (2017) -
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
द्वारा: Xue, L, और अन्य
प्रकाशित: (2005)