Chemical cross-linking stabilizes native-like HIV-1 envelope glycoprotein trimer antigens
Major neutralizing antibody immune evasion strategies of the HIV-1 envelope glycoprotein (Env) trimer include conformational and structural instability. Stabilized soluble trimers such as BG505 SOSIP.664 mimic the structure of virion-associated Env but nevertheless sample different conformational st...
| Hoofdauteurs: | , , , , , , , , , , , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
American Society for Microbiology
2015
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