Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc3Man9GlcNAc2 precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycoside hy...
Hauptverfasser: | Sobala, Ł, Fernandes, PZ, Hakki, Z, Thompson, AJ, Howe, JD, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, TD, Alonzi, DS, Williams, SJ, Davies, GJ |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
National Academy of Sciences
2020
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