Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc3Man9GlcNAc2 precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycoside hy...

书目详细资料
Main Authors:	Sobala, Ł, Fernandes, PZ, Hakki, Z, Thompson, AJ, Howe, JD, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, TD, Alonzi, DS, Williams, SJ, Davies, GJ
格式:	Journal article
语言:	English
出版:	National Academy of Sciences 2020

相似书籍

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase.
由: Thompson, A, et al.
出版: (2012)

Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.
由: Butters, T, et al.
出版: (2009)

Therapeutic targets for inhibitors of glycosylation.
由: Alonzi, D, et al.
出版: (2011)

Norman Manea dialogue avec Hélène Lenz
由: Norman Manea, et al.
出版: (2013-12-01)

DISCOVERY OF A SELECTIVE LYSOSOMAL ALPHA-MANNOSIDASE INHIBITOR FROM AN IMINO-SUGAR LIBRARY
由: Chang, Y, et al.
出版: (2014)

Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation.
由: Crispin, M, et al.
出版: (2007)

Recollection of the Native Space as Autobiographical Pretext: Norman Manea, “The Hooligan’s Return”
由: Irina Ghiorghiasa
出版: (2011-06-01)

Targeting glycosylation as a therapeutic approach.
由: Dwek, R, et al.
出版: (2002)

The application of aqueous two-phase systems to oligosaccharide synthesis by alpha-mannosidase catalysed glycosyl transfer reactions.
由: Bartlett, T, et al.
出版: (1992)

The Unseen Faces of Translation. Insights into the English and Spanish Translations of Norman Manea’s The Hooligan’s Return
由: Mihaela Vancea
出版: (2022-07-01)

Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.
由: Long, E, et al.
出版: (2010)

[ARTÍCULO RETRACTADO] Integración de minorías en Europa. La propuesta de Elham Manea
由: Paz Molero Hernández
出版: (2018-12-01)

Safety evaluation of the food enzyme mannan endo‐1,4‐β‐mannosidase from the genetically modified Aspergillus niger strain NZYM‐NM
由: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), et al.
出版: (2022-04-01)

Safety evaluation of the food enzyme mannan endo‐1,4‐β‐mannosidase from the genetically modified Trichoderma reesei strain RF6232
由: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), et al.
出版: (2022-08-01)

Glycosylation: disease targets and therapy.
由: Zitzmann, N, et al.
出版: (2005)

STRUCTURE AND SYNTHESIS OF FUCOSIDASE AND MANNOSIDASE INHIBITORS
由: Fleet, G
出版: (1989)

Efficient recombinant expression and secretion of a thermostable GH26 mannan endo-1,4-β-mannosidase from <it>Bacillus licheniformis </it>in <it>Escherichia coli</it>
由: Haltrich Dietmar, et al.
出版: (2010-04-01)

Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase.
由: Michael D L Suits, et al.
出版: (2010-02-01)

Transferrin coupled azanthraquinone enhances the killing effect on trypanosomes. The role of lysosomal mannosidase
由: Nok A.J., et al.
出版: (2002-12-01)

Cloning, expression in <it>Pichia pastoris</it>, and characterization of a thermostable GH5 mannan endo-1,4-<it>β</it>-mannosidase from <it>Aspergillus niger </it>BK01
由: Sigoillot Jean-Claude, et al.
出版: (2009-11-01)

Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells
由: Perera, N, et al.
出版: (2022)

In vivo production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expression with Endo-β-N-acetylglucosaminidase H (Endo H) of Streptomyces plicatus.
由: Tarlan Mamedov, et al.
出版: (2017-01-01)

Exploring the potential of iminosugars as antivirals for Crimean-Congo haemorrhagic fever virus, using the surrogate Hazara virus: liquid-chromatography-based mapping of viral N-glycosylation and in vitro antiviral assays
由: Tyrrell, BE, et al.
出版: (2023)

The structural basis of the inhibition of human alpha-mannosidases by azafuranose analogues of mannose.
由: Winchester, B, et al.
出版: (1993)

Iminosugar antivirals: the therapeutic sweet spot
由: Alonzi, D, et al.
出版: (2017)

A trimeric glycosylated GH45 cellulase from the red abalone (Haliotis rufescens) exhibits endo and exoactivity.
由: L Joshua Hernández-Benítez, et al.
出版: (2024-01-01)

Assessing antigen structural integrity through glycosylation analysis of the SARS-CoV-2 viral spike
由: Brun, J, et al.
出版: (2021)

Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays
由: Beatrice E. Tyrrell, et al.
出版: (2023-03-01)

Ligand binding by the immunoglobulin superfamily recognition molecule CD2 is glycosylation-independent.
由: Davis, S, et al.
出版: (1995)

STRUCTURE ACTIVITY RELATIONSHIP OF SWAINSONINE - INHIBITION OF HUMAN ALPHA-MANNOSIDASES BY SWAINSONINE ANALOGS
由: Dibello, I, et al.
出版: (1989)

Pyrrolidine Derivatives as New Inhibitors of ?-Mannosidases and Growth Inhibitors of Human Cancer Cells
由: Hélène Fiaux, et al.
出版: (2006-04-01)

Emerging principles for the therapeutic exploitation of glycosylation.
由: Dalziel, M, et al.
出版: (2014)

IL CLOWN – UNA METAFORA PER L’IDENTITÀ DELL’ARTISTA NEL CIRCO DELLA STORIA E DELL’ESISTENZA IN MATEI VIȘNIEC E NORMAN MANEA
由: Emilia DAVID
出版: (2023-03-01)

Structural insights into the broad-spectrum antiviral target endoplasmic reticulum alpha-glucosidase II
由: Zitzmann, N, et al.
出版: (2018)

Maria Sabina Draga-Alexandru y Dragoş Manea, eds. Religious narratives in contemporary culture: between cultural memory and transmediality. Leiden; Boston, Brill, 2021, x, 220 pp.
由: Dana Bădulescu
出版: (2023-11-01)

The bovine viral diarrhoea virus: a model for the study of antiviral molecules interfering with N-glycosylation and folding of envelope glycoprotein
由: Durantel, D, et al.
出版: (2015)

Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV‑2 Viral Spike
由: Juliane Brun, et al.
出版: (2021-03-01)

1,4-Dideoxy-1,4-imino-D-mannitol inhibits glycoprotein processing and mannosidase.
由: Palamarczyk, G, et al.
出版: (1985)

IMINOHEPTITOLS AS GLYCOSIDASE INHIBITORS - SYNTHESIS OF, AND MANNOSIDASE AND FUCOSIDASE INHIBITION BY, ALPHA-HOMOMANNOJIRMYCIN AND 6-EPI-HOMOMANNOJIRMYCIN
由: Bruce, I, et al.
出版: (1989)

INHIBITION OF ALPHA-MANNOSIDASE ACTIVITY BY 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL
由: Elbein, A, et al.
出版: (1985)