Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc3Man9GlcNAc2 precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycoside hy...

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Bibliographic Details
Main Authors: Sobala, Ł, Fernandes, PZ, Hakki, Z, Thompson, AJ, Howe, JD, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, TD, Alonzi, DS, Williams, SJ, Davies, GJ
Format: Journal article
Language:English
Published: National Academy of Sciences 2020