Disruption of c-MYC binding and chromosomal looping involving genetic variants associated with ankylosing spondylitis upstream of the RUNX3 promoter
<strong>Background:</strong> Ankylosing Spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex aetiology and high heritability, involving more than 100 genetic associations. These include several AS-associated single nucleotide polymorphisms (SNPs) upstream of...
Main Authors: | Cohen, CJ, Davidson, C, Selmi, C, Bowness, P, Knight, JC, Wordsworth, BP, Vecellio, M |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2022
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