The genetic landscape of renal complications in type 1 diabetes.

Diabetes is the leading cause of ESRD. Despite evidence for a substantial heritability of diabetic kidney disease, efforts to identify genetic susceptibility variants have had limited success. We extended previous efforts in three dimensions, examining a more comprehensive set of genetic variants in...

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Hlavní autoři: Sandholm, N, Van Zuydam, N, Ahlqvist, E, Juliusdottir, T, Deshmukh, H, Rayner, N, Di Camillo, B, Forsblom, C, Fadista, J, Ziemek, D, Salem, R, Hiraki, L, Pezzolesi, M, Trégouët, D, Dahlström, E, Valo, E, Oskolkov, N, Ladenvall, C, Marcovecchio, M, Cooper, J, Sambo, F, Malovini, A, Manfrini, M, McKnight, A, Lajer, M, Harjutsalo, V, Gordin, D, Parkkonen, M, Tuomilehto, J, Lyssenko, V, McKeigue, P, Rich, S, Brosnan, M, Fauman, E, Bellazzi, R, Rossing, P, Hadjadj, S, Krolewski, A, Paterson, A, Florez, J, Hirschhorn, J, Maxwell, A, Dunger, D, Cobelli, C, Colhoun, H, Groop, L, McCarthy, M, Groop, P
Médium: Journal article
Jazyk:English
Vydáno: American Society for Nephrology 2016