An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.

Inhibitors of the protease of HIV-1 have been used successfully for the treatment of HIV-1-infected patients and AIDS disease. We tested whether these protease inhibitory drugs exerted effects in addition to their antiviral activity. Here, we show in mice infected with lymphocytic choriomeningitis v...

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Detalles Bibliográficos
Main Authors: André, P, Groettrup, M, Klenerman, P, de Giuli, R, Booth, B, Cerundolo, V, Bonneville, M, Jotereau, F, Zinkernagel, R, Lotteau, V
Formato: Journal article
Idioma:English
Publicado: 1998

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