An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.
Inhibitors of the protease of HIV-1 have been used successfully for the treatment of HIV-1-infected patients and AIDS disease. We tested whether these protease inhibitory drugs exerted effects in addition to their antiviral activity. Here, we show in mice infected with lymphocytic choriomeningitis v...
Main Authors: | André, P, Groettrup, M, Klenerman, P, de Giuli, R, Booth, B, Cerundolo, V, Bonneville, M, Jotereau, F, Zinkernagel, R, Lotteau, V |
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格式: | Journal article |
语言: | English |
出版: |
1998
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