Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant
Structure-based vaccine design has been used to develop immunogens that display conserved neutralization sites on pathogens such as HIV-1, respiratory syncytial virus (RSV), and influenza. Improving the immunogenicity of these designed immunogens with adjuvants will require formulations that do not...
Main Authors: | Francica, JR, Lynn, GM, Laga, R, Joyce, MG, Ruckwardt, TJ, Morabito, KM, Chen, M, Chaudhuri, R, Zhang, B, Sastry, M, Druz, A, Ko, K, Choe, M, Pechar, M, Georgiev, IS, Kueltzo, LA, Seymour, LW, Mascola, JR, Kwong, PD, Graham, BS, Seder, RA |
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格式: | Journal article |
语言: | English |
出版: |
American Chemical Society
2016
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