Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection.
CMV-specific memory CD8(+) T cells accumulate over time to reach high frequencies amongst peripheral blood lymphocytes - a phenomenon termed 'memory inflation'. Using tetramer staining on samples from a large number of subjects and multivariate regression analysis, we were able to relate t...
Main Authors: | Northfield, J, Lucas, M, Jones, H, Young, N, Klenerman, P |
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Format: | Journal article |
Language: | English |
Published: |
2005
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