Considerations for the design, analysis and presentation of in vivo studies

Important statistical principles and key methodological challenges in the study design, statistical analysis, and reporting of results from in vivo studies are considered along with the underlying statistical principles and practical suggestions. The importance of pre-specifying endpoints and analys...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Cook, J, Ranstam, J
Format: Journal article
Udgivet: Elsevier 2016
Beskrivelse
Summary:Important statistical principles and key methodological challenges in the study design, statistical analysis, and reporting of results from in vivo studies are considered along with the underlying statistical principles and practical suggestions. The importance of pre-specifying endpoints and analysis, the common underlying assumption of statistically independent observations, sample size considerations, and multiplicity issues are considered. Additionally, the reporting of results and graphical presentations are also discussed.