Rheumatoid arthritis association at 6q23.
The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-5) - 5 x 10(-7) in a genome-wide association screen. One, rs6920220, was unequivocally replicated (trend P = 1.1 x 10(-8)) in a validation study, as described...
| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , |
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| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
2007
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| _version_ | 1826280732828368896 |
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| author | Thomson, W Barton, A Ke, X Eyre, S Hinks, A Bowes, J Donn, R Symmons, D Hider, S Bruce, I Wilson, A Marinou, I Morgan, A Emery, P Carter, A Steer, S Hocking, L Reid, D Wordsworth, P Harrison, P Strachan, D Worthington, J |
| author_facet | Thomson, W Barton, A Ke, X Eyre, S Hinks, A Bowes, J Donn, R Symmons, D Hider, S Bruce, I Wilson, A Marinou, I Morgan, A Emery, P Carter, A Steer, S Hocking, L Reid, D Wordsworth, P Harrison, P Strachan, D Worthington, J |
| author_sort | Thomson, W |
| collection | OXFORD |
| description | The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-5) - 5 x 10(-7) in a genome-wide association screen. One, rs6920220, was unequivocally replicated (trend P = 1.1 x 10(-8)) in a validation study, as described here. This SNP maps to 6q23, between the genes oligodendrocyte lineage transcription factor 3 (OLIG3) and tumor necrosis factor-alpha-induced protein 3 (TNFAIP3). |
| first_indexed | 2024-03-07T00:18:08Z |
| format | Journal article |
| id | oxford-uuid:7b8e978a-2e08-462c-8c52-00bc3aefbde3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:18:08Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:7b8e978a-2e08-462c-8c52-00bc3aefbde32022-03-26T20:51:28ZRheumatoid arthritis association at 6q23.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7b8e978a-2e08-462c-8c52-00bc3aefbde3EnglishSymplectic Elements at Oxford2007Thomson, WBarton, AKe, XEyre, SHinks, ABowes, JDonn, RSymmons, DHider, SBruce, IWilson, AMarinou, IMorgan, AEmery, PCarter, ASteer, SHocking, LReid, DWordsworth, PHarrison, PStrachan, DWorthington, JThe Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-5) - 5 x 10(-7) in a genome-wide association screen. One, rs6920220, was unequivocally replicated (trend P = 1.1 x 10(-8)) in a validation study, as described here. This SNP maps to 6q23, between the genes oligodendrocyte lineage transcription factor 3 (OLIG3) and tumor necrosis factor-alpha-induced protein 3 (TNFAIP3). |
| spellingShingle | Thomson, W Barton, A Ke, X Eyre, S Hinks, A Bowes, J Donn, R Symmons, D Hider, S Bruce, I Wilson, A Marinou, I Morgan, A Emery, P Carter, A Steer, S Hocking, L Reid, D Wordsworth, P Harrison, P Strachan, D Worthington, J Rheumatoid arthritis association at 6q23. |
| title | Rheumatoid arthritis association at 6q23. |
| title_full | Rheumatoid arthritis association at 6q23. |
| title_fullStr | Rheumatoid arthritis association at 6q23. |
| title_full_unstemmed | Rheumatoid arthritis association at 6q23. |
| title_short | Rheumatoid arthritis association at 6q23. |
| title_sort | rheumatoid arthritis association at 6q23 |
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