Rheumatoid arthritis association at 6q23.

Rheumatoid arthritis association at 6q23.

The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-5) - 5 x 10(-7) in a genome-wide association screen. One, rs6920220, was unequivocally replicated (trend P = 1.1 x 10(-8)) in a validation study, as described...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Thomson, W, Barton, A, Ke, X, Eyre, S, Hinks, A, Bowes, J, Donn, R, Symmons, D, Hider, S, Bruce, I, Wilson, A, Marinou, I, Morgan, A, Emery, P, Carter, A, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Strachan, D, Worthington, J
Format:	Journal article
Sprog:	English
Udgivet:	2007

Lignende værker

Whole genome association studies of rheumatoid arthritis and replication of identified susceptibility loci
af: Ke, X, et al.
Udgivet: (2007)

A re-evaluation of three putative functional single nucleotide polymorphisms in rheumatoid arthritis.
af: Plant, D, et al.
Udgivet: (2009)

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.
af: Barton, A, et al.
Udgivet: (2008)

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.
af: Orozco, G, et al.
Udgivet: (2011)

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.
af: Eyre, S, et al.
Udgivet: (2010)

No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort.
af: Eyre, S, et al.
Udgivet: (2010)

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
af: Barton, A, et al.
Udgivet: (2008)

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population.
af: Eyre, S, et al.
Udgivet: (2010)

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
af: Burr, M, et al.
Udgivet: (2010)

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
af: Orozco, G, et al.
Udgivet: (2010)

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.
af: Barton, A, et al.
Udgivet: (2009)

Corrigendum: Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes
af: Barton, A, et al.
Udgivet: (2010)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
af: Orozco, G, et al.
Udgivet: (2009)

Corrigendum: Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23
af: Orozco, G, et al.
Udgivet: (2010)

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes (vol 18, pg 2518, 2009)
af: Barton, A, et al.
Udgivet: (2010)

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
af: Orozco, G, et al.
Udgivet: (2014)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23 (vol 18, pg 2693, 2009)
af: Orozco, G, et al.
Udgivet: (2010)

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.
af: McClure, A, et al.
Udgivet: (2009)

PREDICTING THE RISK OF RHEUMATOID ARTHRITIS AND ITS AGE OF ONSET: MODELLING GENETIC RISK VARIANTS WITH SMOKING
af: Scott, I, et al.
Udgivet: (2013)

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci (vol 48, pg 1369, 2009)
af: McClure, A, et al.
Udgivet: (2011)

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.
af: Morgan, A, et al.
Udgivet: (2009)

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking
af: Scott, I, et al.
Udgivet: (2013)

Reevaluation of the Interaction Between HLA-DRB1 Shared Epitope Alleles, PTPN22, and Smoking in Determining Susceptibility to Autoantibody-Positive and Autoantibody-Negative Rheumatoid Arthritis in a Large UK Caucasian Population (vol 60, pg 2565, 2009)
af: Morgan, A, et al.
Udgivet: (2011)

A replication study of the UK rheumatoid arthritis whole genome screen.
af: Barton, A, et al.
Udgivet: (2002)

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.
af: McAllister, K, et al.
Udgivet: (2013)

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
af: Hinks, A, et al.
Udgivet: (2009)

Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.
af: Eyre, S, et al.
Udgivet: (2004)

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
af: Hinks, A, et al.
Udgivet: (2012)

A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population.
af: Mackie, S, et al.
Udgivet: (2012)

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.
af: Bowes, J, et al.
Udgivet: (2010)

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
af: Bowes, J, et al.
Udgivet: (2010)

Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.
af: Hinks, A, et al.
Udgivet: (2010)

REFINEMENT OF THE CRH HAPLOTYPE IN RHEUMATOID ARTHRITIS
af: Steer, S, et al.
Udgivet: (2004)

Linkage analysis of potential rheumatoid arthritis non-HLA susceptibility loci.
af: MacKay, K, et al.
Udgivet: (2000)

STRATIFICATION ANALYSIS REVEALS EVIDENCE FOR LINKAGE IN SUBSETS OF 378 RA ASP FAMILIES
af: Eyre, S, et al.
Udgivet: (2002)

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom.
af: MacKay, K, et al.
Udgivet: (2002)

THE HLA CLASS II ASSOCIATIONS OF RHEUMATOID-ARTHRITIS CONFER SEVERITY NOT SUSCEPTIBILITY
af: Gough, A, et al.
Udgivet: (1992)

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom (vol 46,pg 632, 2002)
af: MacKay, K, et al.
Udgivet: (2002)

Replication of association of the interleukin 23 receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets.
af: Chen-Xu, M, et al.
Udgivet: (2012)

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.
af: Raychaudhuri, S, et al.
Udgivet: (2009)