Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.

BACKGROUND: Guidance is needed on best medical management for advanced HIV disease with multidrug resistance (MDR) and limited retreatment options. We assessed two novel antiretroviral (ARV) treatment approaches in this setting. METHODS AND FINDINGS: We conducted a 2×2 factorial randomized open labe...

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Hlavní autoři: Holodniy, M, Brown, S, Cameron, D, Kyriakides, T, Angus, B, Babiker, A, Singer, J, Owens, D, Anis, A, Goodall, R, Hudson, F, Piaseczny, M, Russo, J, Schechter, M, Deyton, L, Darbyshire, J
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2011