The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR

The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR

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The NADPH cytochrome P450 reductase (CPR), a diflavin enzyme, catalyzes the electron transfer (ET) from NADPH to the substrate P450. The crystal structures of mammalian and yeast CPRs show a compact organization for the two domains containing FMN (flavin mononucleotide) and FAD (flavin adenine dinuc...

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Bibliographic Details
Main Authors:	Vincent, B, Morellet, N, Fatemi, F, Aigrain, L, Truan, G, Guittet, E, Lescop, E
Format:	Journal article
Language:	English
Published:	2012

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