The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR

The NADPH cytochrome P450 reductase (CPR), a diflavin enzyme, catalyzes the electron transfer (ET) from NADPH to the substrate P450. The crystal structures of mammalian and yeast CPRs show a compact organization for the two domains containing FMN (flavin mononucleotide) and FAD (flavin adenine dinuc...

詳細記述

書誌詳細
主要な著者: Vincent, B, Morellet, N, Fatemi, F, Aigrain, L, Truan, G, Guittet, E, Lescop, E
フォーマット: Journal article
言語:English
出版事項: 2012