Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.
The emerging notion of environment-induced reprogramming of Foxp3(+) regulatory T (Treg) cells into helper T (Th) cells remains controversial. By genetic fate mapping or adoptive transfers, we have identified a minor population of nonregulatory Foxp3(+) T cells exhibiting promiscuous and transient F...
Hlavní autoři: | Miyao, T, Floess, S, Setoguchi, R, Luche, H, Fehling, H, Waldmann, H, Huehn, J, Hori, S |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2012
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