Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

The emerging notion of environment-induced reprogramming of Foxp3(+) regulatory T (Treg) cells into helper T (Th) cells remains controversial. By genetic fate mapping or adoptive transfers, we have identified a minor population of nonregulatory Foxp3(+) T cells exhibiting promiscuous and transient F...

Полное описание

Библиографические подробности
Главные авторы: Miyao, T, Floess, S, Setoguchi, R, Luche, H, Fehling, H, Waldmann, H, Huehn, J, Hori, S
Формат: Journal article
Язык:English
Опубликовано: 2012