Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

<h4>Background</h4> <p>Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting. Many oncolytic viruses combine targeted cytotoxicity to cancer cells with a proinflammatory ce...

Full description

Bibliographic Details
Main Authors: Lei, J, Jacobus, E, Taverner, W, Fisher, K, Hemmi, S, West, K, Slater, L, Lilley, F, Brown, A, Champion, B, Duffy, M, Seymour, L
Format: Journal article
Language:English
Published: BioMed Central 2018

Similar Items

Similar Items