Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

<h4>Background</h4> <p>Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting. Many oncolytic viruses combine targeted cytotoxicity to cancer cells with a proinflammatory ce...

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Dettagli Bibliografici
Autori principali:	Lei, J, Jacobus, E, Taverner, W, Fisher, K, Hemmi, S, West, K, Slater, L, Lilley, F, Brown, A, Champion, B, Duffy, M, Seymour, L
Natura:	Journal article
Lingua:	English
Pubblicazione:	BioMed Central 2018

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