Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C.

Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C.

HLA class I-mediated selection of immune escape mutations in functionally important Gag epitopes may partly explain slower disease progression in HIV-1-infected individuals with protective HLA alleles. To investigate the impact of Gag function on disease progression, the replication capacities of vi...

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Bibliographic Details
Main Authors:	Wright, J, Novitsky, V, Brockman, M, Brumme, Z, Brumme, C, Carlson, J, Heckerman, D, Wang, B, Losina, E, Leshwedi, M, van der Stok, M, Maphumulo, L, Mkhwanazi, N, Chonco, F, Goulder, P, Essex, M, Walker, B, Ndung'u, T
Format:	Journal article
Language:	English
Published:	2011

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