Gene expression signatures as biomarkers of tumour hypoxia
Hypoxia is a feature of most solid tumours and is associated with a poor prognosis. The hypoxic environment can reduce the efficacy of radiotherapy and some chemotherapeutics, and has been investigated extensively as a therapeutic target. The clinical use of hypoxia-targeting treatment will benefit...
Hauptverfasser: | , , , |
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Format: | Journal article |
Sprache: | English |
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Elsevier
2015
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