Gene expression signatures as biomarkers of tumour hypoxia

Hypoxia is a feature of most solid tumours and is associated with a poor prognosis. The hypoxic environment can reduce the efficacy of radiotherapy and some chemotherapeutics, and has been investigated extensively as a therapeutic target. The clinical use of hypoxia-targeting treatment will benefit...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Harris, B, Barberis, A, West, C, Buffa, F
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2015