Gene expression signatures as biomarkers of tumour hypoxia

Hypoxia is a feature of most solid tumours and is associated with a poor prognosis. The hypoxic environment can reduce the efficacy of radiotherapy and some chemotherapeutics, and has been investigated extensively as a therapeutic target. The clinical use of hypoxia-targeting treatment will benefit...

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Detalles Bibliográficos
Autores principales: Harris, B, Barberis, A, West, C, Buffa, F
Formato: Journal article
Lenguaje:English
Publicado: Elsevier 2015