Selective targeting of homologous recombination deficiency
<p>Homologous recombination (HR) is a key DNA repair pathway essential for cell viability. Counter-intuitively, HR deficiency can trigger carcinogenesis. Understanding the mechanisms that allow the rampant proliferation of HR-deficient tumour cells is crucial for the development of improved th...
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| Format: | Thesis |
| Language: | English |
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2014
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