Selective targeting of homologous recombination deficiency
<p>Homologous recombination (HR) is a key DNA repair pathway essential for cell viability. Counter-intuitively, HR deficiency can trigger carcinogenesis. Understanding the mechanisms that allow the rampant proliferation of HR-deficient tumour cells is crucial for the development of improved th...
מחבר ראשי: | Zimmer, J |
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מחברים אחרים: | Tarsounas, M |
פורמט: | Thesis |
שפה: | English |
יצא לאור: |
2014
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נושאים: |
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