Selective targeting of homologous recombination deficiency

<p>Homologous recombination (HR) is a key DNA repair pathway essential for cell viability. Counter-intuitively, HR deficiency can trigger carcinogenesis. Understanding the mechanisms that allow the rampant proliferation of HR-deficient tumour cells is crucial for the development of improved th...

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Podrobná bibliografie
Hlavní autor: Zimmer, J
Další autoři: Tarsounas, M
Médium: Diplomová práce
Jazyk:English
Vydáno: 2014
Témata: