Selective targeting of homologous recombination deficiency

<p>Homologous recombination (HR) is a key DNA repair pathway essential for cell viability. Counter-intuitively, HR deficiency can trigger carcinogenesis. Understanding the mechanisms that allow the rampant proliferation of HR-deficient tumour cells is crucial for the development of improved th...

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书目详细资料
主要作者: Zimmer, J
其他作者: Tarsounas, M
格式: Thesis
语言:English
出版: 2014
主题: