Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Stromal-derived intratumoural heterogeneity (ITH) has been shown to undermine molecular stratification of patients into appropriate prognostic/predictive subgroups. Here, using several clinically relevant colorectal cancer (CRC) gene expression signatures, we assessed the susceptibility of these sig...

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書誌詳細
主要な著者: Dunne, P, Alderdice, M, O'Reilly, P, Roddy, A, McCorry, A, Richman, S, Maughan, T, McDade, S, Johnston, P, Longley, D, Kay, E, McArt, D, Lawler, M
フォーマット: Journal article
言語:English
出版事項: Springer Nature 2017