NRAS, FLT3 and TP53 mutations in patients with myelodysplastic syndrome and a del(5q).
Mutations of the NRAS and TP53 genes and internal tandem duplication (ITD) of the FLT3 gene are among the most frequently observed molecular abnormalities in the myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). We sought to determine the incidence of these abnormalities in patients...
Main Authors: | Fidler, C, Watkins, F, Bowen, D, Littlewood, T, Wainscoat, J, Boultwood, J |
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Format: | Journal article |
Language: | English |
Published: |
2004
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