Total synthesis of antascomicin B.

(Chemical Equation Presented) The structurally enticing antascomicin B (1), which exhibits potent immunosuppressant-antagonizing properties, has a complex polyketide structure. Key steps in its enantioselective total synthesis include a transannular catechol-templated Dieckmann reaction to assemble...

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Main Authors: Brittain, D, Griffiths-Jones, C, Linder, MR, Smith, M, McCusker, C, Barlow, J, Akiyama, R, Yasuda, K, Ley, S
格式: Journal article
语言:English
出版: 2005