Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers.
Aside from apolipoprotein E (APOE), genetic risk factors for β amyloid deposition in cognitively intact individuals remain to be identified. Brain derived neurotrophic factor (BDNF) modulates neural plasticity, which has been implicated in Alzheimer's disease. We examined in cognitively normal...
Hauptverfasser: | Adamczuk, K, De Weer, A, Nelissen, N, Chen, K, Sleegers, K, Bettens, K, Van Broeckhoven, C, Vandenbulcke, M, Thiyyagura, P, Dupont, P, Van Laere, K, Reiman, E, Vandenberghe, R |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2013
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