MyD88-dependent autoimmune disease in Lyn-deficient mice.
Recent evidence suggests that systemic autoimmune disease depends on signals from TLR ligands, but little is known about how TLR-dependent pathways lead to the loss of self tolerance in vivo. To address this, we have examined the role of TLR signaling in Lyn-deficient mice, which develop an autoimmu...
| Main Authors: | , , , , , |
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| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
2007
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