MyD88-dependent autoimmune disease in Lyn-deficient mice.

Recent evidence suggests that systemic autoimmune disease depends on signals from TLR ligands, but little is known about how TLR-dependent pathways lead to the loss of self tolerance in vivo. To address this, we have examined the role of TLR signaling in Lyn-deficient mice, which develop an autoimmu...

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Bibliografiska uppgifter
Huvudupphovsmän: Silver, K, Crockford, T, Bouriez-Jones, T, Milling, S, Lambe, T, Cornall, R
Materialtyp: Journal article
Språk:English
Publicerad: 2007