Model-driven experimentation: A new approach to understand mechanisms of tertiary lymphoid tissue formation, function, and therapeutic resolution
The molecular and cellular processes driving the formation of secondary lymphoid tissues have been extensively studied using a combination of mouse knockouts, lineage-specific reporter mice, gene expression analysis, immunohistochemistry, and flow cytometry. However, the mechanisms driving the forma...
Автори: | Butler, J, Cosgrove, J, Alden, K, Timmis, J, Coles, M |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
Frontiers Media
2017
|
Схожі ресурси
Схожі ресурси
-
Pairing experimentation and computational modelling to understand the role of tissue inducer cells in the development of lymphoid organs
за авторством: Kieran eAlden, та інші
Опубліковано: (2012-07-01) -
Simulating CXCR5 Dynamics in Complex Tissue Microenvironments
за авторством: Jason Cosgrove, та інші
Опубліковано: (2021-09-01) -
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology
за авторством: Nayar, S, та інші
Опубліковано: (2019) -
Stromal cells in tertiary lymphoid structures: a novel pathogenic paradigm and therapeutic target in Sjogren's syndrome
за авторством: Nayar, S, та інші
Опубліковано: (2017) -
STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
за авторством: Walter J Storkus, та інші
Опубліковано: (2021-02-01)