A systematic review of outcome reporting in colorectal cancer surgery.

AIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prosp...

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Prif Awduron: Whistance, R, Forsythe, R, McNair, A, Brookes, S, Avery, K, Pullyblank, A, Sylvester, P, Jayne, D, Jones, J, Brown, J, Coleman, MG, Dutton, S, Hackett, R, Huxtable, R, Kennedy, R, Morton, D, Oliver, A, Russell, A, Thomas, MG, Blazeby, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2013
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author Whistance, R
Forsythe, R
McNair, A
Brookes, S
Avery, K
Pullyblank, A
Sylvester, P
Jayne, D
Jones, J
Brown, J
Coleman, MG
Dutton, S
Hackett, R
Huxtable, R
Kennedy, R
Morton, D
Oliver, A
Russell, A
Thomas, MG
Blazeby, J
author_facet Whistance, R
Forsythe, R
McNair, A
Brookes, S
Avery, K
Pullyblank, A
Sylvester, P
Jayne, D
Jones, J
Brown, J
Coleman, MG
Dutton, S
Hackett, R
Huxtable, R
Kennedy, R
Morton, D
Oliver, A
Russell, A
Thomas, MG
Blazeby, J
author_sort Whistance, R
collection OXFORD
description AIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prospective studies reporting clinical outcomes of CRC surgery. Outcomes were listed verbatim, categorized into broad groups (outcome domains) and examined for a definition (an appropriate textual explanation or a supporting citation). Outcome reporting was considered inconsistent if results of the outcome specified in the methods were not reported. Outcome reporting was compared between randomized and nonrandomized studies. RESULTS: Of 5644 abstracts, 194 articles (34 randomized and 160 nonrandomized studies) were included reporting 766 different clinical outcomes, categorized into seven domains. A mean of 14 ± 8 individual outcomes were reported per study. 'Anastomotic leak', 'overall survival' and 'wound infection' were the three most frequently reported outcomes in 72, 60 and 44 (37.1%, 30.9% and 22.7%) studies, respectively, and no single outcome was reported in every publication. Outcome definitions were significantly more often provided in randomized studies than in nonrandomized studies (19.0% vs 14.9%, P = 0.015). One-hundred and twenty-seven (65.5%) papers reported results of all outcomes specified in the methods (randomized studies, n = 21, 61.5%; nonrandomized studies, n = 106, 66.2%; P = 0.617). CONCLUSION: Outcome reporting in CRC surgery lacks consistency and method. Improved standards of outcome measurement are recommended to permit data synthesis and transparent cross-study comparisons.
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spelling oxford-uuid:7ccbc8e2-81c1-417e-9c5c-d218c1788b0f2022-03-26T20:59:25ZA systematic review of outcome reporting in colorectal cancer surgery.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7ccbc8e2-81c1-417e-9c5c-d218c1788b0fEnglishSymplectic Elements at Oxford2013Whistance, RForsythe, RMcNair, ABrookes, SAvery, KPullyblank, ASylvester, PJayne, DJones, JBrown, JColeman, MGDutton, SHackett, RHuxtable, RKennedy, RMorton, DOliver, ARussell, AThomas, MGBlazeby, JAIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prospective studies reporting clinical outcomes of CRC surgery. Outcomes were listed verbatim, categorized into broad groups (outcome domains) and examined for a definition (an appropriate textual explanation or a supporting citation). Outcome reporting was considered inconsistent if results of the outcome specified in the methods were not reported. Outcome reporting was compared between randomized and nonrandomized studies. RESULTS: Of 5644 abstracts, 194 articles (34 randomized and 160 nonrandomized studies) were included reporting 766 different clinical outcomes, categorized into seven domains. A mean of 14 ± 8 individual outcomes were reported per study. 'Anastomotic leak', 'overall survival' and 'wound infection' were the three most frequently reported outcomes in 72, 60 and 44 (37.1%, 30.9% and 22.7%) studies, respectively, and no single outcome was reported in every publication. Outcome definitions were significantly more often provided in randomized studies than in nonrandomized studies (19.0% vs 14.9%, P = 0.015). One-hundred and twenty-seven (65.5%) papers reported results of all outcomes specified in the methods (randomized studies, n = 21, 61.5%; nonrandomized studies, n = 106, 66.2%; P = 0.617). CONCLUSION: Outcome reporting in CRC surgery lacks consistency and method. Improved standards of outcome measurement are recommended to permit data synthesis and transparent cross-study comparisons.
spellingShingle Whistance, R
Forsythe, R
McNair, A
Brookes, S
Avery, K
Pullyblank, A
Sylvester, P
Jayne, D
Jones, J
Brown, J
Coleman, MG
Dutton, S
Hackett, R
Huxtable, R
Kennedy, R
Morton, D
Oliver, A
Russell, A
Thomas, MG
Blazeby, J
A systematic review of outcome reporting in colorectal cancer surgery.
title A systematic review of outcome reporting in colorectal cancer surgery.
title_full A systematic review of outcome reporting in colorectal cancer surgery.
title_fullStr A systematic review of outcome reporting in colorectal cancer surgery.
title_full_unstemmed A systematic review of outcome reporting in colorectal cancer surgery.
title_short A systematic review of outcome reporting in colorectal cancer surgery.
title_sort systematic review of outcome reporting in colorectal cancer surgery
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