A systematic review of outcome reporting in colorectal cancer surgery.
AIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prosp...
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| Fformat: | Journal article |
| Iaith: | English |
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2013
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| _version_ | 1826280972065177600 |
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| author | Whistance, R Forsythe, R McNair, A Brookes, S Avery, K Pullyblank, A Sylvester, P Jayne, D Jones, J Brown, J Coleman, MG Dutton, S Hackett, R Huxtable, R Kennedy, R Morton, D Oliver, A Russell, A Thomas, MG Blazeby, J |
| author_facet | Whistance, R Forsythe, R McNair, A Brookes, S Avery, K Pullyblank, A Sylvester, P Jayne, D Jones, J Brown, J Coleman, MG Dutton, S Hackett, R Huxtable, R Kennedy, R Morton, D Oliver, A Russell, A Thomas, MG Blazeby, J |
| author_sort | Whistance, R |
| collection | OXFORD |
| description | AIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prospective studies reporting clinical outcomes of CRC surgery. Outcomes were listed verbatim, categorized into broad groups (outcome domains) and examined for a definition (an appropriate textual explanation or a supporting citation). Outcome reporting was considered inconsistent if results of the outcome specified in the methods were not reported. Outcome reporting was compared between randomized and nonrandomized studies. RESULTS: Of 5644 abstracts, 194 articles (34 randomized and 160 nonrandomized studies) were included reporting 766 different clinical outcomes, categorized into seven domains. A mean of 14 ± 8 individual outcomes were reported per study. 'Anastomotic leak', 'overall survival' and 'wound infection' were the three most frequently reported outcomes in 72, 60 and 44 (37.1%, 30.9% and 22.7%) studies, respectively, and no single outcome was reported in every publication. Outcome definitions were significantly more often provided in randomized studies than in nonrandomized studies (19.0% vs 14.9%, P = 0.015). One-hundred and twenty-seven (65.5%) papers reported results of all outcomes specified in the methods (randomized studies, n = 21, 61.5%; nonrandomized studies, n = 106, 66.2%; P = 0.617). CONCLUSION: Outcome reporting in CRC surgery lacks consistency and method. Improved standards of outcome measurement are recommended to permit data synthesis and transparent cross-study comparisons. |
| first_indexed | 2024-03-07T00:21:46Z |
| format | Journal article |
| id | oxford-uuid:7ccbc8e2-81c1-417e-9c5c-d218c1788b0f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:21:46Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:7ccbc8e2-81c1-417e-9c5c-d218c1788b0f2022-03-26T20:59:25ZA systematic review of outcome reporting in colorectal cancer surgery.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7ccbc8e2-81c1-417e-9c5c-d218c1788b0fEnglishSymplectic Elements at Oxford2013Whistance, RForsythe, RMcNair, ABrookes, SAvery, KPullyblank, ASylvester, PJayne, DJones, JBrown, JColeman, MGDutton, SHackett, RHuxtable, RKennedy, RMorton, DOliver, ARussell, AThomas, MGBlazeby, JAIM: Evaluation of surgery for colorectal cancer (CRC) is necessary to inform clinical decision-making and healthcare policy. The standards of outcome reporting after CRC surgery have not previously been considered. METHOD: Systematic literature searches identified randomized and nonrandomized prospective studies reporting clinical outcomes of CRC surgery. Outcomes were listed verbatim, categorized into broad groups (outcome domains) and examined for a definition (an appropriate textual explanation or a supporting citation). Outcome reporting was considered inconsistent if results of the outcome specified in the methods were not reported. Outcome reporting was compared between randomized and nonrandomized studies. RESULTS: Of 5644 abstracts, 194 articles (34 randomized and 160 nonrandomized studies) were included reporting 766 different clinical outcomes, categorized into seven domains. A mean of 14 ± 8 individual outcomes were reported per study. 'Anastomotic leak', 'overall survival' and 'wound infection' were the three most frequently reported outcomes in 72, 60 and 44 (37.1%, 30.9% and 22.7%) studies, respectively, and no single outcome was reported in every publication. Outcome definitions were significantly more often provided in randomized studies than in nonrandomized studies (19.0% vs 14.9%, P = 0.015). One-hundred and twenty-seven (65.5%) papers reported results of all outcomes specified in the methods (randomized studies, n = 21, 61.5%; nonrandomized studies, n = 106, 66.2%; P = 0.617). CONCLUSION: Outcome reporting in CRC surgery lacks consistency and method. Improved standards of outcome measurement are recommended to permit data synthesis and transparent cross-study comparisons. |
| spellingShingle | Whistance, R Forsythe, R McNair, A Brookes, S Avery, K Pullyblank, A Sylvester, P Jayne, D Jones, J Brown, J Coleman, MG Dutton, S Hackett, R Huxtable, R Kennedy, R Morton, D Oliver, A Russell, A Thomas, MG Blazeby, J A systematic review of outcome reporting in colorectal cancer surgery. |
| title | A systematic review of outcome reporting in colorectal cancer surgery. |
| title_full | A systematic review of outcome reporting in colorectal cancer surgery. |
| title_fullStr | A systematic review of outcome reporting in colorectal cancer surgery. |
| title_full_unstemmed | A systematic review of outcome reporting in colorectal cancer surgery. |
| title_short | A systematic review of outcome reporting in colorectal cancer surgery. |
| title_sort | systematic review of outcome reporting in colorectal cancer surgery |
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